岛屿神经解剖网络预测整个感知意识
Alan S R Fermin1, Takafumi Sasaoka1, Toru Maekawa1
1Center for Brain, Mind and Kansei Sciences Research, Hiroshima University, 734-8553, Hiroshima city, Hiroshima, Japan.
Heliyon
|July 31, 2023
概括
间接感知意识 (IA),即对身体信号的感知,与内灰质体积和特定的大脑网络有关. 这一发现可能会为焦虑障碍的新干预提供信息.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 心理健康研究 心理健康研究
背景情况:
- 间接感知意识 (IA) 涉及感知身体内部信号,与情绪调节和精神健康障碍有关.
- 一个拟议的大脑整体感受网络 (BIN) 连接了像杏仁体,胰岛和ACC这样的区域,但经验证据有限.
研究的目的:
- 研究IA,大脑结构 (灰质体积和结构共变网络) 和心理健康 (焦虑和抑郁症状) 之间的关系.
- 测试IA是由一个涉及杏仁体,胰岛和ACC的BIN调解的假设.
主要方法:
- 利用公开的数据集与神经成像和心跳检测任务数据用于客观IA测量.
- 采用Voxel-Based Morphometry (VBM) 来分析关键大脑区域的灰质体积 (GMV) 和结构共变性网络 (SCN).
- 使用验证的问卷评估抑郁症状和焦虑.
主要成果:
- 在IA和状态焦虑之间发现了积极的相关性,但没有抑郁症状.
- 左前半岛灰质体积与IA正相关.
- 特定的岛内结构协同变异网络 (右侧背部细粒体岛与左侧背部和超细粒体岛) 与IA积极相关.
结论:
- 这些发现揭示了整感觉意识,岛内灰质体积和岛内结构共变网络之间的新关联.
- 这些结果表明神经成像干预的潜力,例如神经反,以增强IA并预防焦虑症等心理健康问题.
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