胆乳胰岛素补充剂不会影响新生Holstein公牛的免疫球蛋白G吸收
K S Hare1, K M Wood1, R Sargent2
1Department of Animal Biosciences, Animal Science and Nutrition, Ontario Agricultural College, University of Guelph, Guelph, ON, Canada N1G 1Y2.
JDS communications
|July 31, 2023
概括
大奶粉中的胰岛素度没有影响新生荷尔斯坦公牛的免疫球蛋白G (IgG) 吸收. 这项研究发现,乳牛奶中高水平的胰岛素和基底水平的胰岛素都没有影响IgG的吸收,这表明没有有害或有益的影响.
科学领域:
- 兽医免疫学 兽医免疫学
- 新生儿生理学 新生儿生理学
- 类动物营养 类动物营养
背景情况:
- 胰岛素抑制免疫球蛋白G (IgG) 吸收的作用在其他新生儿物种中已知.
- 了解牛的这种机制对于新生儿小牛的健康和被动免疫转移至关重要.
研究的目的:
- 为了研究不同胆管胰岛素度对新生Holstein公牛犊的IgG吸收的影响.
- 为了确定胆乳中胰岛素水平的升高是否会影响IgG吸收的效率.
主要方法:
- 48只霍尔斯坦牛犊被随机分配给基底,5倍或10倍基底胰岛素度的胆乳.
- 产后2小时,14小时和26小时,小牛被以体重7%的胆乳.
- 在养后600分钟内测量血清IgG度;计算了曲线下的增量面积 (I-AUC) 和明显吸收效率 (AEA).
主要成果:
- 大奶粉的组成 (脂肪,蛋白质,乳糖,IgG) 在治疗组中一致.
- 血清IgG度,I-AUC和AEA没有受到腹胰岛素水平的显著影响.
- 没有观察到高胆固醇胰岛素对IgG吸收的有害或促进作用.
结论:
- 结肠直肠胰岛素度不会影响新生Holstein公牛的IgG吸收.
- 这些发现表明,操纵胆管胰岛素不太可能增强小牛的被动免疫转移.
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