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化学与酶合成的基于多糖醇的 Ester:它们的表面活性之间的比较
Jacopo F A A Amari1, Sara Sangiorgio1, Eleonora Pargoletti1
1Department of Chemistry, University of Milan, Via Golgi 19, 20133 Milan, Italy.
ACS omega
|July 31, 2023
概括
聚糖醇酸 (PGSAEs) 的酶合成为有效的表面活性剂提供了一条可持续的途径. 优化条件和可回收20个循环的生物催化剂证明了它们的工业潜力.
科学领域:
- 绿色化学 绿色化学
- 生物催化剂是一种生物催化剂.
- 表面活性剂科学 表面活性剂科学
背景情况:
- 聚糖醇脂肪酸 (PGFAEs) 是来自可再生资源的多功能表面活性剂.
- 它们可调节的水友性-脂友性平衡 (HLB) 使它们在各种行业中具有价值.
- 酶合成为化学化提供了一个可持续的替代方案.
研究的目的:
- 通过酶化化合成多糖醇-2酸 (PG2SAEs).
- 优化反应条件并研究生物催化剂的可重复使用性.
- 为了比较酶合成的PG2SAE与化学合成的PG2SAE的特性.
主要方法:
- 聚糖醇-2 (PG2) 和酸 (SA) 的酶化化使用固定脂酶Novozym 435.
- 在无溶剂系统中优化温度,反应剂比率和酶负荷.
- 使用染色学和质谱学对产品进行表征;通过界面张力和乳液研究评估表面活性剂的特性.
主要成果:
- 优化反应条件实现了PG2SAEs的高效合成.
- 生物催化剂 (Novozym 435) 在20个回收循环中保持了显著的活性.
- 酶合成的PG2SAE表现出与化学合成产品相比的或更高的乳化和稳定性.
结论:
- 酶合成为生产PGSAEs提供了一种可持续和高效的方法.
- 优化过程和可重复使用的生物催化剂凸显了这种绿色方法的经济可行性.
- 通过酶途径产生的PGSAE显示出对O/W乳液的卓越表面活性剂性能.
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