加拿大单纯疹病毒1型的流行病学:系统性审查,元分析和元回归
Sawsan AlMukdad1,2, Manale Harfouche1,2, Uzma S Farooqui1
1Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation - Education City, Doha, Qatar.
Frontiers in public health
|July 31, 2023
概括
加拿大的简单疹病毒1型 (HSV-1) 流行病学显示,从口服获取转向生殖器获取,在成年人中患病率增加. 随着时间的推移,HSV-1血清流行率和生殖器疹检测率都在上升.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 简单疹病毒1型 (HSV-1) 是一种常见的病毒感染,具有重大公共卫生影响.
- 了解加拿大的HSV-1流行病学对于制定有针对性的预防和控制策略至关重要.
研究的目的:
- 描述加拿大的简单疹病毒1型 (HSV-1) 的当前流行病学.
- 分析HSV-1血清流行和生殖器疹检测的趋势.
主要方法:
- 在2021年12月6日之前对HSV-1出版物的系统审查,遵守PRISMA指南.
- 在从22项研究中提取的数据上进行了元分析和元回归.
主要成果:
- 综合平均HSV-1血清流行率在儿童中为19.1%,在成人中为51.4%,随着年龄的增长而增加.
- 血清流行率每年增加1.02倍.
- 在生殖器疹中检测HSV-1的平均比例为37.4%,每年增加1.04倍,特别是在妇女和年轻人中.
结论:
- 加拿大HSV-1流行病学表明,从口服获取转向生殖器获取,特别是在年轻人中.
- 随着时间的推移,HSV-1的血清流行率和归因于HSV-1的生殖器疹病例比例都在增加.
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