肥胖成年人的微血管变化通过光学连贯性断层扫描检测血管图谱
Goksu Alacamli1, Sema Tamer Kaderli2, Sultan Edebali3
1Ophthalmology Department, Trakya University Faculty of Medicine, Education and Research Hospital, Edirne, Turkey.
Romanian journal of ophthalmology
|July 31, 2023
概括
在成年人中,肥胖与视神经头血管密度降低和子叶冠状腺厚度增加有关. 光学相干断层扫描血管图 (OCT-A) 揭示了肥胖个体的这些微血管变化.
科学领域:
- 眼科医生 眼科 眼科
- 血管生物学 血管生物学
- 肥胖问题研究研究
背景情况:
- 肥胖是一个全球性的健康问题,与各种系统性并发症有关.
- 视网膜的微血管变化可能是系统代谢变化的早期指标.
研究的目的:
- 为了比较肥胖和非肥胖成年人之间的视网膜微血管参数,使用光学一致性断层扫描血管学 (OCT-A).
主要方法:
- 一项前性,受控,非随机化研究,涉及92名受试者 (184只眼睛),根据身体质量指数 (BMI) 分为正常体重,超重和肥胖群体.
- 眼部检查包括视敏度,眼部运动,裂口灯和眼底检查.
- 在6.00x6.00毫米的斑点区域进行了OCT-A,以评估血管密度 (VD),状血管区域 (FAZ),胆毛囊 (CCP) 区域,亚状胆道厚度 (SCT) 和中央斑点厚度 (CMT).
主要成果:
- 与正常体重组相比,超重和肥胖组观察到视神经头部 (ONH) 的VD明显较低.
- 在超重和肥胖个体中,肌下部胆道厚度 (SCT) 显著更高.
- 两组之间没有发现黄斑体内疾病,FAZ,CCP区域或CMT的显著差异.
结论:
- OCT-A是检测与肥胖相关的视网膜和胸膜中的微血管变化的一个有价值的工具.
- 虽然 fundus 检查本身有局限性,但OCT-A 提供了与肥胖相关的血管变化的可预测见解.
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