与非常老年COVID-19患者30天死亡率相关的变量
Yunli Xing1, Ying Sun1, Mei Tang1
1Department of Geriatrics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
非常老的COVID-19患者的死亡率很高. 功能状态 (巴特尔指数),血清肌素,白细胞计数,D-二次体水平和皮质类固醇使用独立预测这种脆弱人群的存活率.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
背景情况:
- 高龄是严重COVID-19的重要危险因素.
- 患有COVID-19的非常老年患者 (≥80岁) 的死亡风险因素在很大程度上是未知的.
研究的目的:
- 调查COVID-19诊断的非常老年患者的临床特征和死亡率之间的关系.
- 在这个特定的人口群体中确定30天死亡率的独立预测因素.
主要方法:
- 追溯分析了80岁及以上的181名住院COVID-19患者.
- 数据收集包括社会人口统计因素,临床变量和30天生存率.
- 采用多变量分析来确定死亡率的独立预测因素.
主要成果:
- 在80岁及以上的患者中,总体30天死亡率为35.9%.
- 在80-90岁和90岁以上的年龄组之间没有观察到死亡率的显著差异.
- 死亡率的独立预测因素包括较低的巴塞尔指数,血清肌素和白细胞计数的升高,较高的D-二聚合物水平和皮质类固醇使用 (保护性).
结论:
- 患有COVID-19的非常老年患者面临着相当大的死亡风险.
- 功能状态,特定的实验室标记 (血清肌素,WBC,D-二次体) 和皮质类固醇治疗是关键的独立因素,与死亡率相关的这一群体.
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