在接受肺部康复治疗的COVID-19患者中甲状腺激素的变化
Laura Croce1,2, Elisabetta Zampogna3, Francesca Coperchini1
1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Frontiers in endocrinology
|July 31, 2023
概括
肺部康复可以改善严重的COVID-19患者的甲状腺功能 (FT3) 和身体能力. 康复组在6分钟步行测试和短物理性能电池中增加了FT3和表现更好.
科学领域:
- 内分泌学 在内分泌学.
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
背景情况:
- 严重的COVID-19可能导致长期残疾和甲状腺功能改变,通常与非甲状腺疾病综合征 (NTIS) 相关.
- 肺部康复是一种公认的干预措施,用于改善COVID-19后患者的功能结果.
研究的目的:
- 与对照组相比,在接受呼吸系统康复的COVID-19患者中调查甲状腺功能参数.
- 在随访期间评估甲状腺功能和身体表现的变化.
主要方法:
- 一项涉及39名COVID-19后患者的比较研究,分为康复组 (n=20) 和对照组 (n=19).
- 评估在基线 (T0) 和3个月后的随访 (T1) 进行,评估甲状腺功能 (TSH,FT4,FT3) 和身体表现 (6MWT,SPPB).
主要成果:
- 康复组在T0时表现出较低的FT3,并接受了更密集的护理 (通风,更长的住院时间,并发性疾病).
- 只有康复组在T1显示FT3的显著增加,以及6MWT和SPPB的改进.
- 对照组在甲状腺功能参数上没有显著变化,但改善了6MWT结果.
结论:
- 在严重的COVID-19患者中,肺部康复与改善甲状腺功能有关,特别是FT3水平的增加.
- 在随访期间,康复导致功能能力的增强,包括步行距离和身体表现的改善.
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