心脏参与多质神经炎和皮质神经炎:诊断方法
Agnieszka Trybuch1, Beata Tarnacka2
1Department of Rehabilitation, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Reumatologia
|July 31, 2023
概括
异形性炎症性肌肉病症,如多聚炎和皮肤肌炎,可以影响心脏. 使用Troponin I和心电图早期发现心脏问题对于管理这些罕见的自身免疫性疾病至关重要.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 异常性炎症性肌肉病变 (IIM),包括多质神经炎 (PM) 和皮质神经炎 (DM),是罕见的自身免疫性疾病.
- 在IIM中心脏参与是预后不佳的重要预测因素,也是导致死亡的主要原因.
- 了解心血管表现对于患者管理至关重要.
研究的目的:
- 审查有关IIM患者心血管表现现的当前知识.
- 突出诊断方法和预后因素与心脏参与与IIM相关.
- 综合了2021年12月之前发表的英语文献的研究结果.
主要方法:
- 对IIM中心血管症状研究的文献综述.
- 在2021年12月之前选择英语出版物.
- 对临床症状,诊断标志物和成像发现的分析.
主要成果:
- 在IIM的临床心脏症状往往是非特异性的,需要差异诊断.
- 热素I被确定为在IIM中评估心肌损伤的特定和首选生物标志物.
- 心电图通常显示非特异性ST-T段变化,心声图经常显示左心室扩张功能障碍.
结论:
- 心血管参与是IIM的一个关键问题,影响预后和死亡率.
- 特定的诊断工具,如Troponin I和心电图,对于评估IIM患者的心脏健康非常有价值.
- 虽然先进的技术可以检测到亚临床心肌异常,但它们的预后意义需要进一步调查.
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