勃起器脊柱肌肉含量与慢性心力衰竭及其严重程度之间的关联
Hao Zhang1, Weiwei Hu1, Mengxuan Yuan2
1Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, PR China.
ESC heart failure
|July 31, 2023
概括
勃起脊柱肌 (ESM) 含量在慢性心力衰竭 (CHF) 患者中显著降低. 较低的ESM含量可以独立预测心血管衰竭的发作和严重程度,提供诊断价值.
科学领域:
- 心脏病学 心脏病学
- 骨肌肉生理学 骨肌肉生理学
- 心脏衰竭中的生物标志物
背景情况:
- 慢性心力衰竭 (CHF) 与骨肌肉质量减少有关.
- 勃起脊柱肌 (ESM) 在心血管衰竭的背景下没有得到广泛的研究.
研究的目的:
- 研究勃起脊柱肌 (ESM) 含量与慢性心力衰竭 (CHF) 的发展之间的关联.
- 确定ESM内容是否可以预测CHF的严重程度.
主要方法:
- 一组652名患者被分为对照组和CHF组.
- 根据LVEF,CHF患者进一步被分为HFpEF和HFrEF.
- 使用接收器运行曲线 (ROC) 分析来评估ESM的预测能力.
主要成果:
- 与对照组相比,CHF患者的ESM含量显著降低.
- 在HFrEF患者中,ESM含量明显低于HFpEF患者.
- 确定ESM作为一个独立的预测器,用于CHF发病 (OR0.713) 和严重程度 (OR0.514).
结论:
- 勃起脊柱肌 (ESM) 含量是预测慢性心力衰竭 (CHF) 开始的一个有价值的指标.
- 在预测CHF的严重程度方面,ESM的内容也具有显著的价值,区分HFpEF和HFrEF.
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