在丸癌幸存者中使用EORTC QLQ-TC26的性功能:一个多机构,横截面研究
Juntaro Koyama1, Shinichi Yamashita1, Kenichi Kakimoto2
1Department of Urology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
概括
丸癌症幸存者经历逆皮质淋巴结解剖 (RPLND) 经历性功能降低,特别是射精功能. 与非神经节约方法相比,神经节约RPLND技术显著改善了性结果.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 性医学性医学性医学性医学
背景情况:
- 丸癌 (TC) 幸存者面临影响生活质量的长期副作用.
- 性功能障碍是TC幸存者治疗后的一个重要问题.
研究的目的:
- 通过使用EORTC QLQ-TC26问卷来评估日本TC幸存者的性功能.
- 分析包括RPLND在内的特定治疗对性功能的影响.
主要方法:
- 这是一项多机构,跨部门的研究,涉及567名日本的TC幸存者.
- 参与者完成了EORTC QLQ-TC26以评估治疗后的性功能.
- 进行统计分析以确定治疗影响.
主要成果:
- 性功能,特别是射精功能,与监测或单独化疗相比,在化疗后的逆腺淋巴结解剖 (PC-RPLND) 后显著降低.
- 神经节约RPLND保留了术后的射精功能,比非神经节约手术更好.
- 特别是没有神经节约的RPLND是射精功能障碍的显著预测因素.
结论:
- 在TC幸存者的性功能和活动在RPLND后减少,特别是当不使用神经节约技术时.
- 在RPLND期间保持神经功能对于维持TC幸存者的性健康至关重要.
相关概念视频
Disorders of the Male Reproductive System
463
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
463
Male Sexual Response: Erection & Ejaculation
2.8K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
2.8K
Infertility in Males
295
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
295
Testes: Gross Anatomy
2.4K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
2.4K
Testes: Histology
1.0K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
The spermatogenic cells, responsible for producing sperm, are...
1.0K


