切断外科手术治疗或缓解医学难以治疗的发作:一项回顾性研究
Saya Koh1, Takehiro Uda1,2, Noritsugu Kunihiro2
1Departments of1Neurosurgery and.
Journal of neurosurgery. Pediatrics
|July 31, 2023
概括
切断手术有效地治疗医学上难治的发作 (ES),75.6%的患者获得了良好的结果. 然而,发作复发在13个月内很常见,这凸显了持续管理的必要性.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 医学上难治的发作 (ES) 可以通过手术治疗.
- 包括息手术在内的ES手术的术后结果需要进一步了解.
研究的目的:
- 为了确定ES在切断手术后有利的术后结果的比例.
- 确定与有利的ES结果相关的术前因素.
- 分析ES复发的时间在切断外科手术后治疗和息指示.
主要方法:
- 对41名因医学上难以治疗的ES而接受切断手术的患者进行了回顾性研究 (2015年5月 - 2021年4月).
- 患者接受了焦点发病ES的叶片断裂或一般化/未知发病ES的体切除术 (CC),具有潜在的二次叶片断裂.
- 使用国际病联盟的分类来评估结果;有利的结果被定义为1-4类.
主要成果:
- 75.6%的患者取得了良好的术后ES结果.
- 较长的发作持续时间,高心律失常和MRI阳性结果与较差的结果相关 (p < 0.05).
- 在60.9%的患者中发生ES复发,通常在手术后13个月内发生.
结论:
- 脱离手术是医疗上难以治疗的ES的有效治疗方法,无论最初的发作发作分类如何.
- 手术前的因素,如持续时间,心律失常和MRI检测结果,都会影响手术成功.
- 手术后ES的早期复发需要持续监测和管理策略.
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