脱口术后的高流量鼻氧疗法与慢性阻塞性肺部疾病的非侵入性通风相对应的非侵入性通风
Pankti Sheth Ketan1, Rohit Kumar2, Mahendran Aj3
1Department of Pulmonary, Critical Care and Sleep Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi. panktisheth10991@gmail.com.
概括
高流量鼻腔管 (HFNC) 与非侵入性通风 (NIV) 一样有效,用于断奶患有慢性阻塞性肺病和超性呼吸衰竭的患者. 这两种方法都显示出在输出管后治疗失败率相似.
科学领域:
- 肺部病理学 肺部病理学
- 关键护理医学 关键护理医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 建议非侵入性通风 (NIV) 用于断奶的超气呼吸衰竭患者.
- 高流量鼻管 (HFNC) 对于断奶的有效性仍然不确定.
- 慢性阻塞性肺病 (COPD) 恶化经常导致需要机械通风的超呼吸衰竭.
研究的目的:
- 为了比较HFNC与NIV在预防COPD患者的脱口后呼吸衰竭方面的有效性.
- 评估治疗失败率和重症监护室 (ICU) 停留时间.
- 评估患者对HFNC和NIV的耐受性.
主要方法:
- 一个单一中心,前性,随机的比较研究.
- 62名COPD患者患有高口腔呼吸衰竭,入侵后通风,被随机分为HFNC或NIV组.
- 主要结局:在输出管后72小时内治疗失败,定义为重新输入管或切换支持模式.
主要成果:
- 治疗失败发生在HFNC组的26.67%和NIV组的25% (p=0.881).
- 两组之间在ICU停留时间上没有显著差异 (HFNC:5.47±2.26天与NIV:6.56±3.39天,p=0.376).
- 与NIV相比,HFNC表现出更好的治疗耐受性.
结论:
- 在预防COPD患者的脱口后呼吸衰竭方面,HFNC与NIV无差.
- HFNC提供了一种可行的,耐受性良好的替代NIV用于断奶.
- 这些发现支持使用HFNC来治疗COPD患者的呼吸衰竭.
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