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内牙治疗对内皮功能障碍和亚临床动脉样硬化的影响 - 一项前性干预研究
Nishant Chauhan1, Shweta Mittal2, Sanjay Tewari2
1Post Graduate Institute of Dental Sciences, Rohtak, Haryana, 124001, India. catchnishu619@gmail.com.
Clinical oral investigations
|July 31, 2023
概括
牙周内治疗显著改善流介导扩张 (FMD) 和降低动脉内膜介质厚度 (c-IMT) 在牙周顶部牙周炎 (AP) 患者中. 这表明治疗AP可能有助于逆转早期心血管疾病 (CVD) 指标.
科学领域:
- 心血管健康 心血管健康
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙周医学 牙周医学
背景情况:
- 牙上部牙周炎 (AP) 是一种常见的牙疾病.
- 早期心血管疾病 (CVD) 标志物可能受到系统因素的影响.
- AP与血管健康之间的联系需要进一步调查.
研究的目的:
- 评估内牙治疗对AP患者血管功能的影响.
- 为了评估治疗后流介导扩张 (FMD) 和动脉内膜介质厚度 (c-IMT) 的变化.
- 为了确定AP治疗是否可以影响早期心血管疾病指标.
主要方法:
- 研究了一组32名患有AP的年轻人,没有心血管疾病.
- 血管评估包括通过超声波进行手臂动脉口腔炎和动脉c-IMT.
- 测量是在基线和内牙治疗后12个月进行的.
主要成果:
- 内牙治疗显著改善了口病的情况,从4.84%提高到7.68% (p<0.05).
- 动脉内心介质厚度 (c-IMT) 从0.62毫米显著降低到0.59毫米 (p<0.05).
- 这些血管改善是在治疗后12个月内观察到的.
结论:
- 内牙治疗对AP患者的血管健康标志物产生积极影响.
- 改善的口病和减少的c-IMT表明早期心血管疾病变化的潜在逆转.
- 牙周膜炎可能是未来心血管疾病的风险因素,需要及时治疗.
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