最新消息 跨导管装置 关闭先天性 Septal 缺陷
Kathleen P Wood1, Gregory A Fleming1, Reid C Chamberlain2
1Division of Pediatric Cardiology, Duke University, Durham, USA.
Current cardiology reports
|July 31, 2023
概括
过导管装置的关闭是许多心房隔膜缺陷 (ASD) 和一些心室隔膜缺陷 (VSD) 的首选,少入侵的选择,提供比手术更好的结果. 对于儿科患者复杂的VSD关闭,需要进一步的创新.
科学领域:
- 心血管医学 心血管医学
- 医疗器械 医疗器械
- 干预心脏病学 干预心脏病学
背景情况:
- 由于改善结果,对于心房隔膜缺陷 (ASDs) 而不是手术修复,设备关闭越来越受青.
- 室腔隔膜缺陷 (VSD) 的跨导管关闭是特定病例的可接受替代方案,但挑战仍然存在.
研究的目的:
- 审查当前用于ASD和VSD的跨导管关闭装置的设备.
- 突出最近的进展,并确定设备关闭疗法的未来创新领域.
主要方法:
- 对ASD和VSD可用的跨导管闭合装置的文献综述.
- 分析临床试验数据,包括ASSURED试验和FDA批准.
主要成果:
- 根据有利的ASSURED试验结果,FDA批准了一种新的透导管ASD关闭装置.
- 与手术相比,对ASD的设备关闭显示出更低的并发症率,更短的住院时间,以及较低的死亡率.
- 过导管VSD关闭面临局限性,特别是对于儿科患者的周膜缺陷,需要进一步的研究和设备开发.
结论:
- 过导管装置的关闭是许多ASD的不那么侵入性,通常是首选的管理策略.
- 进一步的研究和新型设备是必不可少的,以扩大跨导管闭合的安全应用范围,以更广泛的VSDs,特别是儿童群体.
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