纳米药物输送策略用于口服生物增强型奎尔塞丁配方
Esha S Attar1, Vanashree H Chaudhari1, Chaitanya G Deokar1
1Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, N.P. Marg, Matunga, Mumbai, Maharashtra, 400019, India.
European journal of drug metabolism and pharmacokinetics
|July 31, 2023
概括
纳米配方显著提高奎尔塞丁的生物可用性,以增强治疗效果. 奎尔素植物体在抗癌应用和临床益处方面特别有前途.
科学领域:
- 药理学 药理学是指药理学的学科.
- 纳米技术 纳米技术
- 自然产品 自然产品
背景情况:
- 奎尔塞丁是一种黄类化合物,具有广泛的治疗潜力,但由于溶解度低和新陈代谢快速,其口服生物利用性较差.
- 已经探索了各种纳米输送系统,以克服这些局限性,并提高奎尔丁的疗效.
- 奎尔素植物体已经成为一个有前途和商业可用的纳米系统.
研究的目的:
- 审查奎尔丁的治疗应用,重点关注其抗癌潜力.
- 探索纳米奎尔塞丁配方的临床益处.
- 为了突出Quercetin植物体作为输送系统的优势.
主要方法:
- 审查关于奎尔素及其纳米输送系统的现有文献.
- 在体外,体内和人体研究的分析,涉及各种Quercetin纳米系统.
- 专注于氨酸植物体及其在市场上的可用性.
主要成果:
- 已经研究了许多含有素的纳米系统,包括纳米颗粒,脂质体和菌体.
- 奎尔丁植物体显示出越来越多的兴趣和市场存在.
- 纳米quercetin配方显示了改善生物可用性和治疗结果的潜力,特别是在抗癌应用中.
结论:
- 纳米输送系统对于增强quercetin的口服生物可用性和治疗疗效至关重要.
- 奎尔素植物体代表了奎尔素输送的重大进步,并且正在获得引力.
- 进一步研究纳米quercetin配方,特别是用于抗癌疗法是有必要的.
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