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使用全身动态F-FDG-PET在下腹部区区分病理和生理性结直肠吸收的新型客观方法

Toyohiro Kato¹, Hajime Ichikawa^2,3, Takayuki Shibutani³

¹Department of Radiology, Toyohashi Municipal Hospital, 50 Hakken-nishi, Aotake, Toyohashi, Aichi, 441-8570, Japan. kato-toyohiro@toyohashi-mh.jp.

Annals of nuclear medicine

|July 31, 2023

概括

对全身动态PET (WBD-PET) 的质量中心转移距离 (CMSD) 分析有效地区分了病态和生理性结直肠吸收. 这种客观方法显示了与传统的两相PET成像相比较的诊断性能.

科学领域:

核医学就是核医学.
放射学放射学是一门学科.
在瘤学瘤学.

背景情况:

使用正子发射断层扫描 (PET) 在腹腔下部区分病理和生理吸收可能是具有挑战性的.
在早期的PET图像上,偶然的焦点吸收通常需要进一步调查.

研究的目的:

评估全身动态PET (WBD-PET) 的质量中心转移距离 (CMSD) 分析,作为差异化病理和生理结直肠吸收的客观方法.
将WBD-PET上的CMSD分析的诊断性能与传统的两相PET成像进行比较.

主要方法:

在39名患者中对CMSD进行了回顾性分析,这些患者在WBD-PET.上有偶然的焦点吸收.
以组织学或其他成像诊断为基础,将CMSD分为病理和生理组的分类.
接收器操作者特性 (ROC) 分析,以评估CMSD在WBD-PET和双相PET图像上的诊断性能.

主要成果:

总共有66个偶然的焦点吸收被分析,其中19个被归类为病理的,47个被归类为生理的.
对于WBD-PET和双相PET (p < 0.01) 的生理组相比,CMSD在病理吸收组显著较低.
在WBD-PET上的CMSD分析实现了94.7%的灵敏度,89.4%的特异性和89.4%的精度,与两相PET图像相比.

结论:

对WBD-PET的CMSD分析是一种有价值和客观的工具,用于区分病理性和生理性结直肠吸收.
在WBD-PET上CMSD分析的诊断性能与传统的两相PET成像相美.
在WBD-PET上进行CMSD分析可能成为一种新的方法,可以减少对额外延迟成像的需求.

关键词:

质量中心转移距离 (CMSD)诊断性表现诊断性表现病理性吸收病理性吸收生理学吸收时间全身动态正子发射断层扫描 (WBD-PET) 是一种全身动态断层扫描.

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