脏的三指数和二指数扩散分析:呼吸控制采集对扩散参数的影响
Yuki Makino1, Naoki Ohno2, Tosiaki Miyati3
1Radiology Division, Kanazawa University Hospital, 13-1 Takara-Machi, Kanazawa, Ishikawa, 9208641, Japan.
Radiological physics and technology
|July 31, 2023
概括
呼吸控制获取显著影响扩散参数,这是从intravoxel不连贯运动 (IVIM) 分析中得出的. 这种技术可以提高三指数和双指数模型的测量精度和可重复性.
科学领域:
- 医疗成像医学成像
- 放射学 放射学是一门学科.
- 生物物理学的生物物理.
背景情况:
- 内素不连贯运动 (IVIM) 分析使用扩散权重核磁共振 (MRI) 提供了对组织微结构性质的洞察.
- 了解获取技术对IVIM参数的影响对于准确和可重复的测量至关重要,特别是在像脏这样的器官.
研究的目的:
- 研究呼吸控制 (RT) 与自由呼吸 (FB) 对从三指数和双指数IVIM模型中得出的扩散参数的影响.
- 评估获取方法对脏IVIM参数准确性和可重复性的影响.
主要方法:
- 十名健康的志愿者接受了脏MRI,使用3.0T系统,使用呼吸触发 (RT) 和自由呼吸 (FB) 获取协议.
- 三指数 (计算Dp,Df,Ds,Fp,Ff,Fs) 和双指数 (计算D*,F,D) 的IVIM模型应用于扩散权重图像.
- 在RT和FB采集之间比较了扩散参数的适配精度 (nRMSE) 和可重复性 (RC).
主要成果:
- 与自由呼吸 (P <0.05) 相比,通过呼吸控制的获取导致与 perfusion 相关的扩散系数 (Dp 和 D*) 显著降低 (P <0.05).
- RT 采集显示了显著改善的适配精度,这表明三指数和双指数模型的nRMSE值较低 (P < 0.05).
- 对于Dp,Ds,Fs和D*的重复性系数 (RC) 与RT相比较于FB较低,这表明测量一致性得到了增强.
结论:
- 在脏IVIM分析中,呼吸控制的获取显著影响与 perfusion 相关的扩散参数.
- 通过RT获取,可以提高IVIM参数测量的准确性和可重复性,使用三指数和双指数模型.
- 这些发现凸显了呼吸运动管理对于脏可靠的定量扩散MRI的重要性.
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