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Updated: Jul 20, 2025

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鼠标适应SARS-CoV-2选择病毒性突变,导致TNF驱动的依赖年龄的严重疾病,与人类相关的病毒性突变

Stefanie M Bader1,2, James P Cooney1,2, Dylan Sheerin1,2

  • 1The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC 3052, Australia.

Proceedings of the National Academy of Sciences of the United States of America
|July 31, 2023
PubMed
概括

研究人员确定了SARS-CoV-2的遗传变化,这些变化会在小鼠中引起严重的COVID-19. 年轻和老年小鼠的不同免疫反应,包括TNF等途径,影响了疾病的严重程度和存活率.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.细胞因子 细胞因子这是一种炎症炎症炎症炎症.适应小鼠适应的小鼠

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