南非PICU的儿科急性呼吸困扰综合征:一个多站点点患病率研究
Brenda M Morrow1,2, Eleonora Lozano Ray1,2, Mignon McCulloch1,2
1Department of Pediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
概括
儿科急性呼吸窘迫综合征 (pARDS) 影响了南非PICU中近三分之一的儿童,比其他地方的患病率明显高. 这凸显了对该地区的pARDS进一步调查的迫切需要.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 呼吸系统医学 呼吸系统医学
- 流行病学 流行病学
背景情况:
- 儿科急性呼吸困扰综合征 (pARDS) 是儿童的危急病.
- 了解pARDS在不同环境中的流行率和特征对于有针对性的干预至关重要.
研究的目的:
- 为了确定儿科急性呼吸困扰综合征 (pARDS) 的患病率.
- 描述在南非儿科重症监护室 (PICU) 诊断出pARDS的儿童的临床特征.
主要方法:
- 进行了一项观察性,多中心,横截面的点患病率研究.
- 在2022年6个月内,南非四个省份的8个PICU收集了数据.
- 2015年儿科急性肺损伤共识会议的标准被用来确定pARDS病例.
主要成果:
- 该研究在310名儿科患者中发现了30.6%的pARDS患病率.
- 与没有pARDS患者相比,患有pARDS患者的死亡风险更高 (5.6%对3.9%).
- 死亡和呼吸道疾病的入院风险增加与pARDS独立相关.
结论:
- 南非的pARDS患病率 (30.6%) 显著高于其他地区.
- 这一发现强调了在南非背景下扩大对pARDS的研究的必要性.
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