视神经头部,外皮和斑点微血管特征在患有单侧伪皮眼镜患者
Ali Safa Balci1, Ihsan Cakir, Cigdem Altan
1University of Health Sciences Turkey, Beyoglu Eye Training and Research Hospital, Beyoglu, Istanbul, Turkey.
Journal of glaucoma
|July 31, 2023
概括
伪脱皮眼镜 (PEXG) 与降低胆道血管度指数 (CVI) 和毛细血管流量有关. 即使没有PEX的眼睛也显示CVI下降,这表明PEXG可能是双边疾病.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 冠状腺微血管学
背景情况:
- 单侧伪皮性玻璃眼 (PEXG) 可能涉及降低胆道血管度指数 (CVI) 和辐射周毛细血管 (RPC) perfusion.
- 双眼的CVI降低表明PEXG可能是双边疾病.
研究的目的:
- 评估患有单侧PEXG的患者双眼中的周周和黄斑胆道微血管和RPC脉络.
- 为了将这些发现与健康的对照眼睛进行比较.
主要方法:
- 分析了48名单边PEXG (PEX+和PEX-) 患者和45名健康对照患者的96只眼睛.
- 冠状血管度指数 (CVI) 是使用增强深度成像光学连贯性断层扫描 (EDI-OCT) 计算的.
- 使用OCT血管学评估了辐射周毛细血管血管层.
主要成果:
- 与PEX和对照组相比,PEX+眼睛的斑点CVI (mCVI) 和周围毛囊CVI (pCVI) 显着较低.
- 与对照组相比,没有PEX (PEX-) 的眼睛显示mCVI和时间pCVI减少.
- 在所有象限中,PEX+眼睛的 perfusion density (PD) 和 flux index (FI) 都明显较低.
结论:
- PEXG与斑点和周围斑点区域的CVI显著降低有关.
- 在PEXG眼中也观察到降低的 perfusion 密度和流量指数.
- 在没有PEX临床症状的眼睛中可能存在下部mCVI和部pCVI.
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