眼睛表面变化在初级开放角视眼镜患者治疗局部抗高血压药物治疗的患者
Catarina Castro1, Ana Marta1,2, João H Marques1
1Department of Ophthalmology, Centro Hospitalar Universitário de Santo António.
Journal of glaucoma
|July 31, 2023
概括
用于治疗青光眼的局部抗高血压药物 (TAH) 显著恶化眼睛表面疾病和干眼症状. 与对照组相比,患者的眼膜质量降低,角膜损伤增加.
科学领域:
- 眼科医生 眼科 眼科
- 眼睛表面疾病 眼睛表面疾病
- 视光眼管理 视光眼管理
背景情况:
- 青光眼的治疗通常涉及局部抗高血压药物 (TAH).
- TAH药物对眼表面和干眼疾病 (DED) 的影响需要进一步调查.
研究的目的:
- 为了评估使用TAH药物对绿眼病患者的眼睛表面特征和DED.
主要方法:
- 一项横截面研究比较了77名接受TAH药物治疗的玻璃眼患者和77名对照患者.
- 评估了眼膜透度,梅博姆腺损失,眼膜稳定性和脂质层厚度.
- 评估了干眼症状 (OSDI),DED (TFOS DEWS II标准) 和角膜染色.
主要成果:
- TAH药物使用者表现出更高的膜透度和梅博姆腺损失.
- 在TAH组中观察到眼膜稳定性降低,脂质层厚度降低,眼半径高度降低.
- 接受TAH药物治疗的玻璃眼患者的DED,严重症状和角膜染色率显着更高.
结论:
- 局部抗高血压药物显著促进绿眼病患者的干眼病.
- TAH药物导致可测量的眼睛表面变化,导致DED症状增加和角膜损伤.
- 临床医生必须考虑TAH药物效应,当管理眼睛表面疾病在青光眼患者.
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