具有可调节的电化学发光-光的双模式传感器平台,用于选择性检测帕拉克瓦特农药
Mengqing Cheng1, Jing Zhang1, Ting Huang1
1JiangXi University of Chinese Medicine, Nan Chang, JiangXi 330004, China.
Food chemistry
|July 31, 2023
概括
这项研究引入了一种新的双模式传感器,用于检测酸盐 (PQ). 传感器使用功能化的金属有机框架,纳米板和铁,为食品安全应用提供高灵敏度和特异性.
科学领域:
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
- 纳米技术纳米技术
背景情况:
- 金属有机框架纳米板 (RuMOFNSs) 具有强大的电化学发光 (ECL) 和光 (FL) 特性.
- 铁作为一种新型信号标记物,对RuMOFNSs具有高效的火效应.
研究的目的:
- 构建一个"信号开关"ECL-FL双模式传感器,用于敏感的帕拉克瓦特 (PQ) 检测.
- 为了利用ECL和FL信号的灭和恢复进行定量PQ确定.
主要方法:
- 功能化的RuMOFNSs的制造.
- 开发一种双模式传感器,使用带有四铁标记的PQ-aptamer DNA.
- 利用PQ和PQ-AptDNA之间的结合相互作用来诱导空间分离和信号恢复.
主要成果:
- 双模式传感器在PQ-Apt DNA的存在下证明了ECL和FL信号的高效灭.
- 在PQ添加后,由于诱导的空间分离,观察到信号恢复.
- 实现了PQ检测的高灵敏度和特异性,检测极限较低 (ECL为0.008 ng/mL,FL为0.059 ng/mL).
结论:
- 拟议的ECL-FL双模式传感器提供了一种敏感和特定的方法来检测帕拉克瓦特.
- 该传感器显示出在食品工业中用于质量和安全监测的巨大应用潜力.
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