了解聚合离子液体吸收剂涂层替代剂对固相微提取中的大麻素和农药亲和力的影响
Victoria R Zeger1, David S Bell2, Jared L Anderson1
1Department of Chemistry, Iowa State University, Ames, IA 50011, United States.
Journal of chromatography. A
|July 31, 2023
概括
开发了新的聚合物离子液 (PIL) 吸收涂层,以改善固相微提取 (SPME) 中的农药和大麻素分离. 结构性修改,如去除芳香基和添加键捐赠体,显著提高了农药-大麻素选择性.
科学领域:
- 分析化学 分析化学
- 材料科学 材料科学 材料科学
- 环境科学 环境科学
背景情况:
- 固相微提取 (SPME) 是分析农药和大麻素的关键技术.
- 开发选择性吸附剂材料对于区分结构相似的化合物至关重要.
- 聚合物离子液体 (PILs) 为先进的提取应用提供可调节的性能.
研究的目的:
- 设计和评估新型聚合物离子液 (PIL) 吸附涂层,以提高SPME中的农药-大麻素选择性.
- 调查PIL结构修改对提取效率和选择性的影响.
- 阐明驱动农药-大麻素分离的关键因素,包括可溶性和吸附剂亲和力.
主要方法:
- 基于现有 PIL 结构的八种新的 PIL 吸附涂层的合成和表征.
- 新的PIL与四个先前报告的PIL用于提取十种农药和六种大麻素的比较.
- 在含有不同甲醇和盐度的水溶液中分析物的溶解度的评估.
- 通过探针分子提取,评估吸附剂对农药和大麻素的亲和力.
主要成果:
- 农药和大麻素溶解度的差异显著影响了提取选择性.
- 缺少芳香成分和添加键供体组的PIL吸附涂层显示出增加的农药-大麻素选择性.
- 吸附剂亲和力与选择性呈现中等相关性,对农药有正相关性,对大麻素有负相关性.
- 确认结相互作用是影响吸附剂亲和力和选择性的关键因素.
结论:
- PIL吸附涂层的结构设计对于在SPME中实现高杀虫剂-大麻素选择性至关重要.
- 尽量减少芳香度和整合键捐赠功能是提高选择性的有效策略.
- 了解分析剂溶解度和剂-分析剂相互作用为优化SPME方法开发提供了一条途径.
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