相关实验视频

Updated: Jul 20, 2025

Collecting Hair Samples for Hair Cortisol Analysis in African Americans

Collecting Hair Samples for Hair Cortisol Analysis in African Americans

Published on: June 10, 2018

唾液和头发皮质醇度之间的纵向关联:系统的比较

Claudio Singh Solorzano¹, Bianca Serwinski², Caterina Grano³

¹Department of Behavioural Science and Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK; Department of Psychology, Sapienza University, Via dei Marsi 78, Rome 00185, Italy.

Psychoneuroendocrinology

|July 31, 2023

概括

头发皮质醇度 (HCC) 可靠地反映了白天其他时间的长期皮质醇输出,而不是早上的皮质醇唤醒反应. 这一发现有助于理解HCC作为压力生物标志物的理解.

科学领域:

心理神经内分泌学心理学
内分泌学在内分泌学.
生物标志物研究生物标志物研究

背景情况:

头发皮质醇度 (HCC) 在心理神经内分泌学中越来越多地用于评估长期压力.
之前的研究显示,与唾液皮质醇比较HCC的混合结果,与日间模式的不清楚相关性.

研究的目的:

评估头发皮质醇度 (HCC) 和唾液皮质醇输出参数之间的对应.
为了确定唾液和头发采样之间的不同时间间隔 (2,4,6周) 对HCC评估的相关性.

主要方法:

一项涉及54名女大学生的纵向研究.
收集了多天的唾液样本,以评估皮质醇唤醒反应 (CAR) 和白天输出 (DAY).
采集了头发样本 (靠近头皮的1厘米) 并分析了HCC,与使用多变量回归的唾液测量相关联.

主要成果:

头发皮质醇度 (HCC) 在所有时间段 (前2,4,6周) 始终与白天唾液皮质醇输出 (DAYauc) 相关.
观察到最强的关联是头发采样前2周的DAYauc和所有时期的聚合DAYauc.
在HCC和皮质醇唤醒反应 (CARauc或CARi) 之间没有发现显著的关联.

结论:

头发皮质醇是一种可靠的追溯生物标志物,用于基底,长期皮质醇分泌,最多在前六周.
HCC反映了白天的皮质醇输出比早晨的皮质醇唤醒反应更接近.
研究结果支持使用HCC作为压力和干预研究中的结果指标.

关键词:

进行比较,比较.皮质醇度皮质醇度头发皮质醇是一种皮质醇.唾液中的皮质醇.

更多相关视频

Extraction and Analysis of Cortisol from Human and Monkey Hair

Extraction and Analysis of Cortisol from Human and Monkey Hair

Published on: January 24, 2014

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers

Published on: December 18, 2013

相关概念视频

Longitudinal Research

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...

Longitudinal Studies

Longitudinal Studies

Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...

Hypothalamic-Pituitary Axis

Hypothalamic-Pituitary Axis

The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.

Correlations

Correlations

Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...

Correlation and Causation

Correlation and Causation

Statistical tests can calculate whether there is a relationship, or correlation, between independent and dependent variables. An indirect relationship of the variables signifies a correlation, while a direct relationship shows causation. If it is determined that no connection exists between the variables, then the correlation is a coincidence.
Correlation versus Causation
If the dependent variable increases or decreases when the independent variable increases, there is a positive or negative...

Salivary Glands and Saliva

Salivary Glands and Saliva

The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...