基于甲基的脱敏剂对通用粘合剂的粘合性能和牙酶活性的影响
Edoardo Mancuso1, Diego Durso1, Claudia Mazzitelli1
1Department of Biomedical and Neuromotor Sciences, DIBINEM, University of Bologna, Alma Mater Studiorum, Via San Vitale 59, Bologna 40125, Italy.
Journal of dentistry
|July 31, 2023
概括
基于甲的脱敏剂显著提高牙结合强度,并随着时间的推移稳定粘合界面. 这种效应似乎独立于矩阵金属蛋白酶抑制,提供更好的长期结合性能.
科学领域:
- 牙科材料科学 牙科材料科学
- 生物材料工程 生物材料工程
- 粘合式牙科 粘合式牙科
背景情况:
- 登丁过敏和结合降解是临床上的重大挑战.
- 基于甲基的药物用于牙治疗,但它们对键强度的长期影响需要进一步研究.
- 通用粘合剂提供了简化应用,但它们与牙预处理的相互作用需要评估.
研究的目的:
- 评估两种基于甲的脱敏剂对微拉伸键强度 (μTBS) 对牙的影响.
- 评估这些脱敏剂对粘合剂界面内源性酶活性的影响.
- 为了比较两种具有牙预处理和没有牙预处理的通用粘合剂在时间上的性能.
主要方法:
- 使用了人类的第三牙,牙表面先用GLUMA无敏化剂 (L) 或GLUMA无敏化剂PowerGel (G) 进行预处理,或没有预处理.
- 标本使用iBond通用 (IBU) 或Adhese Universal (AU) 在自蚀刻模式下进行粘合.
- 微拉力键强度在24小时和1年后进行了测试;在现场发酵镜评估了酶活性.
主要成果:
- 丁丁的预处理,粘合剂类型和老化显著影响了结合强度和酶活性 (P<0.001).
- 附着通用 (AU) 的结合强度高于iBond通用 (IBU) 的结合强度 (P<0.001).
- 使用GLUMA脱敏剂 (L) 的预处理比PowerGel (G) 或对照组 (P<0.001) 产生了更高的结合强度,而老化影响非预处理组最严重 (P<0.001).
- 基线紫外线图显示对照组的光度较低,但在1年后没有观察到差异.
结论:
- 基于甲的脱敏剂提高牙结合强度,稳定粘合界面.
- 观察到的稳定性与矩阵金属蛋白酶抑制没有直接联系.
- 基于甲的脱敏剂与通用粘合剂的预先应用可能会提高长期的临床性能.
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