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通过干扰细胞信号通路来调节MGMT表达

Peiying Bai1, Tengjiao Fan2, Xin Wang3

  • 1Beijing Key Laboratory of Environmental and Viral Oncology, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China.

Biochemical pharmacology
|July 31, 2023
PubMed
概括

对DNA化剂的化学抵抗通常是由O6-甲基瓜氨酸-DNA甲基转移酶 (MGMT) 引起的. 通过细胞信号通路准MGMT表达提供了一种有前途的策略,以提高化疗的疗效和克服瘤耐药性.

关键词:
化剂是一种化剂.细胞信号通路是细胞信号通路.细胞毒性 细胞毒性抑制剂是一种抑制剂.在MGMT中,我们可以看到MGMT.瘤的抗药性 瘤的抗药性

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