通过内镜下膜剖析来治疗食道瘤:经验超过100次连续手术
Josué Aliaga Ramos1,2,3, Yoshinori Morita4, Takashi Toyonaga4
1Department of Gastroenterology, "Jose Agurto Tello-Chosica" Hospital, Lima, Perú.
Clinical endoscopy
|July 31, 2023
概括
在拉丁美洲,内镜下粘膜切割 (ESD) 是一种安全有效的治疗表面食道瘤的方法. 这项研究在100多个案例中证明了它的可行性,实现了高切除率.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 手术瘤学手术瘤学
背景情况:
- 在东方国家,内镜下粘膜切割 (ESD) 是表面食道瘤的标准治疗方法.
- 包括拉丁美洲在内的西方地区对食道ESD的经验由于技术复杂性而有限.
研究的目的:
- 在拉丁美洲中心评估食道ESD的临床应用和结果.
- 在100多个连续病例中评估ESD对表面食道瘤的可行性,安全性和有效性.
主要方法:
- 2009年至2022年间连续接受食道ESD的患者的回顾性分析.
- 评估整体切除,整体切除和治愈切除率,局部复发,不良事件和死亡率.
主要成果:
- 主要针对状细胞癌 (66.6%),高度内皮质瘤 (17.1%) 和腺癌 (11.4%) 进行ESD.
- 整体切除率和整体切除率分别为96.2%和81.0%,治愈切除率为64.8%.
- 不良事件发生在5.7%的病例中,平均随访时间为29.7个月.
结论:
- 消化管ESD是可行的,安全的,在拉丁美洲受过训练的内镜医生进行时临床有效.
- 这项研究支持采用ESD来管理食道表面瘤病变.
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