评估肌肉侵入性膀癌相关健康状况的公用事业
Basil H Chaballout1, Eric M Chang2, Neil R Parikh3
1Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC.
Urologic oncology
|July 31, 2023
概括
患者对肌肉侵入性膀癌治疗的不同功能结果没有显著的偏好,例如阴道管道,新膀或化疗. 这些患者值对于未来的膀癌护理成本效益分析至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
背景情况:
- 在肌肉侵入性膀癌 (MIBC) 决策中,患者对功能结果与瘤结果的偏好尚不清楚.
- 量化患者值对于个性化治疗规划和健康经济评估至关重要.
研究的目的:
- 量化患者对与肌肉侵入性膀癌治疗相关的各种健康状况的偏好.
- 将患者对功能结果的评估与瘤结果进行比较.
主要方法:
- 开发了与MIBC治疗相关的六种假设健康状况的描述,包括不同的手术选择和化疗辐射.
- 利用视觉模拟尺度 (VAS) 和标准博 (SG) 方法来评估患者对这些健康状况的偏好.
- 包括来自一般人口的54个人进行偏好评估.
主要成果:
- 使用VAS或SG方法,在阴道管 (IC),新膀重建 (NB) 和化疗 (CRT) 之间没有发现患者报告值的显著差异.
- 救生囊切除术 (SC) 在VAS上被评为明显低于NB和CRT,但不是SG.
- 复发性/转移性膀癌 (RMBC) 和转移性膀癌 (MBC) 通过这两种方法被评为明显比其他状态更糟糕.
结论:
- 患者对MIBC局部治疗 (IC,NB,CRT) 的偏好在这个一般人群样本中没有显著差异.
- 这些量化患者值可以为未来的膀癌治疗成本效益分析提供信息.
- 了解患者的偏好对于MIBC管理中的共享决策至关重要.
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