瘤微环境中的NR1D1缺乏会通过激活NLRP3炎症酶激活肺瘤的发展

Sun Mi Kim1,2, Yoon Jeon3, Ji Yun Jang3,4

  • 1Graduate School of Cancer Science and Policy, National Cancer Center, Gyeonggi, 10408, Republic of Korea. ksm999@ncc.re.kr.

Cell death discovery
|July 31, 2023
PubMed
概括

核受体Rev-erbα (NR1D1) 通过抑制NLRP3炎症酶,在肺癌中起到瘤抑制作用. NR1D1缺乏促进肺瘤发生,这表明NLRP3炎症酶阻断作为治疗策略.

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