ангиотензиноген, ангиотензин转化酶和基因多态化基因基因多态化基因作为基底细胞癌易感性的生物标志物

Christos Yapijakis1,2,3,4, Iphigenia Gintoni5,6,7, Sevastiana Charalampidou5,6

  • 1Unit of Orofacial Genetics, 1st Department of Pediatrics, National Kapodistrian University of Athens, "Hagia Sophia" Children's Hospital, Athens, Greece. cyapi@med.uoa.gr.

概括

血管增生素 (AGT),血管增生素转化酶 (ACE) 和化学酶 (CMA1) 基因中的某些遗传变异与基底细胞癌 (BCC) 的风险增加有关. 这些多态性与较高的血管素II (AngII) 水平相关,这表明在BCC发育中发挥了作用.

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