99DOTS数字粘附技术对北印度结核病治疗结果的影响:前后研究
Amy Z Chen1, Ravinder Kumar2, R K Baria3
1Everwell Health Solutions, Bangalore, Karnataka, India.
BMC infectious diseases
|July 31, 2023
概括
这项研究发现,在实施99DOTS数字坚持技术后,结核病治疗成功率没有显著差异. 需要进一步的研究来了解技术采用的差异.
科学领域:
- 公共卫生 公共卫生
- 数字卫生技术数字卫生技术
- 结核病研究 结核病研究
背景情况:
- 99DOTS是一种基于手机的数字粘附技术,用于结核病 (TB) 治疗.
- 印度的希马查尔邦在2018年5月为公共医疗保健中的所有药物敏感结核病患者实施了99DOTS.
- 有限的研究评估了99DOTS在改善结核病治疗结果方面的有效性.
研究的目的:
- 评估99DOTS大规模实施对喜马चल邦结核病治疗结果的影响.
- 为了比较数字粘附技术引入之前和之后的治疗成功率.
主要方法:
- 对99DOTS实施前 (2017年2月至10月) 和之后 (2019年7月至2018年3月) 药物敏感结核病患者治疗结果的比较分析.
- 利用了印度国家结核病数据库的数据,包括700多名患者在干预前组和8300多名患者在干预后组.
- 采用多变量后勤回归来评估99DOTS参与和有利治疗结果 (治愈或治疗完成) 之间的关联.
主要成果:
- 干预后组的33.0%的患者至少使用过一次99DOTS,参与频率各不相同.
- 在干预前组的93.1%和干预后组的92.9%观察到有利的治疗结果.
- 在两组之间没有发现有利治疗结果的统计学上显著差异 (OR=0.981,p=0.758),即使经过对共变量进行调整 (aOR=0.970).
结论:
- 在希马查尔邦大规模实施99DOTS并没有导致结核病治疗结果的统计学上显著改善.
- 该研究强调,需要进一步调查影响不同地点数字健康干预措施 (如99DOTS) 采用变量的因素.
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