方法质量和报告质量的COVID-19生活系统审查:一个跨部门研究
Jiefeng Luo1,2,3,4,5, Zhe Chen1,2,3,4,5, Dan Liu1,2,3,4,5
1Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu, China.
BMC medical research methodology
|July 31, 2023
概括
这项研究评估了COVID-19的活体系统审查 (LSR),发现方法和报告质量有很大的改进空间. 关键因素如研究纳入数量和资金影响审查质量,指导未来的研究,以获得更好的证据.
科学领域:
- 医学研究方法论医学研究方法论.
- 基于证据的医学是基于证据的医学.
- 传染病流行病学 传染病流行病学
背景情况:
- 生活系统性审查 (LSRs) 提供持续更新的证据综合.
- 冠状病毒疾病2019 (COVID-19) 的快速传播需要及时,高质量的证据.
- 评估COVID-19 LSRs的质量对于可靠的临床决策至关重要.
研究的目的:
- 评估COVID-19 LSRs的方法和报告质量.
- 确定影响这些审查质量的因素.
主要方法:
- 在六个数据库中系统搜索COVID-19 LSRs.
- 使用测量工具评估系统性审查-2 (AMSTAR-2) 的方法质量评估.
- 评估报告质量使用系统审查和元分析 (PRISMA) 2020年度首选报告项目.
- 线性回归分析以探索影响质量的因素.
主要成果:
- 分析了64个COVID-19的LSR.
- 通过AMSTAR-2评估的方法质量显示,平均有13个"是"答案,其中50%被评为"非常低".
- 通过PRISMA 2020评估的报告质量显示,平均有21个"是"答案,方法和结果报告存在明显的缺陷.
- 更多的纳入研究和注册与更好的方法质量有关.
- 更多的纳入研究和融资来源与报告质量的提高有关.
结论:
- 在COVID-19 LSRs的方法和报告质量方面都需要显著改进.
- 研究人员应该考虑确定了影响质量的因素,以提高未来COVID-19 LSRs的严格性.
- 提高LSR质量对于在公共卫生危机期间生成可靠,基于证据的信息至关重要.
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