视界扫描:英格兰牛结核病控制的下一步是什么?
1Animal and Plant Health Agency, London, UK. James.mccormack@apha.gov.uk.
Irish veterinary journal
|July 31, 2023
概括
英格兰英格兰英格兰英格兰.
科学领域:
- 兽医流行病学 兽医流行病学
- 控制牛结核 控制牛结核 控制牛结核
- 野生动物疾病管理管理
背景情况:
- 英国为期25年的消灭牛结核病 (TB) 战略已经进入第九年.
- 德弗拉对独立的结核病计划审查的回应以及英国首席兽医官的见解为未来的战略提供了信息.
- 目前的结核病控制方法需要加强,以实现根除目标.
研究的目的:
- 探索新的工具和方法,以实现在英国的结核病自由.
- 确定改善牛群结核病风险管理的机会.
- 评估结核病控制新诊断和疫苗接种战略对结核病的潜在影响.
主要方法:
- 对Defra的结核病计划审查反应的分析.
- 考虑使用群体健康评级来加强农民购买决策.
- 探索牛群疫苗接种和DIVA (区分感染者和接种疫苗的动物) 测试.
- 对M. bovis监测的全基因组测序进展的审查.
- 通过有针对性的杀支持的子疫苗接种战略的评估.
主要成果:
- 群体健康评级为农民提供数据,使他们能够进行知情购买,以减少结核病风险.
- 用DIVA测试对牛进行疫苗接种代表了结核病控制的重大潜在进展.
- 全基因组测序为感染追踪和流行病学分析提供了强大的工具.
- 一个案例研究表明,在子中成功消除了疾病,从而使人们能够转向疫苗接种.
结论:
- 结合改进的诊断,疫苗接种,基因组监测和有针对性的野生动物干预措施的多方面的方法对于根除结核病至关重要.
- 有信息的购买,先进的测试和基因组数据可以显著降低牛的结核病风险.
- 过渡到子疫苗接种,通过成功的有针对性的杀,是野生动物结核病管理的关键策略.
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