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Updated: Jul 20, 2025

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
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在N-糖基化ErbB受体中,活跃的背对背二聚体的结构安排由异体二聚化调节

Romina Mashayekh-Poul1, Maryam Azimzadeh-Irani1, Seyedeh Zeinab Masoomi-Nomandan1

  • 1Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.

Molecular biology research communications
|August 1, 2023
PubMed
概括

糖化会影响人体表皮生长因子受体 (EGFR/ErbB) 的二分化,有利于异构分子. 这项研究确定ErbB2-ErbB3是最稳定的二元体,指导新型抗癌药物设计.

关键词:
背对背的二度线.模度化 (Dimerization) 是一个过程.在ErbB受体中,分子建模分子建模

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