儿科机械循环支 - - 综述
Deborah Kozik1, Bahaaldin Alsoufi1
1Department of Cardiovascular and Thoracic Surgery, Norton Children's Hospital, University of Louisville School of Medicine, Louisville, KY USA.
Indian journal of thoracic and cardiovascular surgery
|August 1, 2023
概括
儿科机械循环支持 (MCS) 面临的挑战是由于成年人的设备尺寸不匹配. 开发适合儿童的耐用非常重要,因为儿科末期心力衰竭超过了供体可用性.
科学领域:
- 心血管外科心血管外科
- 儿童心脏病学 儿童心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 机械循环支持 (MCS) 的历史始于1953年的心肺机器.
- 与儿科应用相比,成人末期心力衰竭推动了更快的设备开发.
- 儿科MCS在很大程度上适应了成人设备,对较小的患者提出了与尺寸相关的挑战.
研究的目的:
- 审查儿科患者可用的机械循环支持装置.
- 讨论复杂儿科病例的支持选择,包括单心室解剖学和双心室支持.
- 为了突出儿童专用耐用的日益增长的需求,由于捐赠器官稀缺.
主要方法:
- 关于儿科机械循环支持的现有文献和临床数据的审查.
- 讨论小儿科患者的设备适应和挑战.
- 探索复杂的先天性心脏缺陷的专业支持策略.
主要成果:
- 成人MCS设备通常不适合儿童患者,因为解剖学尺寸的差异.
- 对于耐用,适合儿科的MCS设备存在重大未满足的需求.
- 复杂的病例需要量身定制的方法,包括双心室辅助装置和全人工心脏.
结论:
- 开发新的,适合大小的耐用机械循环支设备对于儿科末期心力衰竭至关重要.
- 正在进行的研究和试验,如儿童,婴儿和新生儿 (PumpKIN) 试验,至关重要.
- 像高级心脏疗法改善结果网络 (ACTION) 这样的注册表对于跟踪结果和推进儿科MCS至关重要.
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