室外冷空气与室温对症状的暴露:一项随机对照试验
Johan N Siebert1,2, Coralie Salomon1, Ilaria Taddeo1
1Department of Pediatric Emergency Medicine, Geneva Children's Hospital, Geneva University Hospitals, Geneva, Switzerland.
Pediatrics
|August 1, 2023
概括
在类固醇开始起作用之前,暴露在寒冷的户外空气中30分钟可以帮助减少儿童的症状. 这种简单的干预方法提供了一种有益的辅助疗法,用于改善儿科患者的.
科学领域:
- 儿科 儿科 儿科
- 紧急医疗 紧急医疗
- 呼吸系统医学 呼吸系统医学
背景情况:
- 是常见的儿科呼吸道疾病,导致上呼吸道阻塞.
- 类固醇对是有效的,但有30分钟的作用.
- 调查辅助疗法来管理形症状至关重要.
研究的目的:
- 评估30分钟冷空气暴露在改善形症状中的有效性.
- 为了确定冷空气暴露是否可以在类固醇作用之前提供快速的症状缓解.
主要方法:
- 一个开放的,随机对照试验,涉及3个月至10岁的儿童,患有 (威斯利得分≥2).
- 参与者接受了口服德克萨梅他,并随机分配到30分钟的室外冷空气 (<10°C) 或室内室内空气中.
- 主要终点是30分钟后Westley Croup评分下降≥2分.
主要成果:
- 与室内空气相比,暴露在室外冷空气中的儿童在形症状上 (49.2%与23.7%) 的改善明显更大.
- 症状改善的风险差异在30分钟后为25.4% (P = .007).
- 中度病例经历了冷空气暴露的最实质性的好处 (风险差异46.1%,P<.001).
结论:
- 30分钟的室外冷空气暴露是口服德甲的有益补充,可减少儿童形症状的严重程度.
- 这种干预措施对中度病例尤为有效.
- 暴露在冷空气中提供了一种快速的,非药物治疗的方法来治疗儿科的症状.
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