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B细胞急性淋巴细胞白血病的生物化学和血液学概况 儿童 儿童
Ammara Khalid1, Mehboob Ahmed, Shahida Hasnain
1Institute of Microbiology and Molecular Genetics, University of the Punjab, Quaid e Azam Campus, Lahore, Pakistan.
Journal of pediatric hematology/oncology
|August 1, 2023
概括
这项研究分析了儿科B细胞急性淋巴细胞白血病 (B-ALL) 的血液学和生物化学概况. 关键发现揭示了B-ALL患者的血液样本变化和基于性别和年龄的显著生化差异.
科学领域:
- 儿科瘤学 儿科瘤学
- 血液学 血液学 血液学
- 临床生物化学 临床生物化学
背景情况:
- B细胞急性淋巴细胞白血病 (B-ALL) 是最常见的儿童白血病.
- 儿童白血病的预后因素包括诊断时间,白细胞计数,年龄和性别.
- 血液学和生化学概况对于在化疗前后评估患者健康至关重要.
研究的目的:
- 在儿科B-ALL病例中评估血液学和生物化学参数.
- 将这些参数与正常参考值进行比较.
- 确定与预后因素 (如年龄和性别) 的潜在相关性.
主要方法:
- 对200例儿科B-ALL病例的分析.
- 评估全血细胞计数 (CBC) 和白血差异计数.
- 评估功能测试,肝功能测试,血清电解质和血清蛋白质.
主要成果:
- 大多数病例是5岁以下的男性.
- 血液学揭示了较低的红细胞,血红蛋白和血小板,与正常人相比,白细胞的数量更高.
- 生物化学概况显示出基于性别和年龄的显著差异,而血液学概况没有显著变化.
结论:
- 儿科B-ALL患者表现出明显的血液学和生化学特征.
- 生物化学参数显示出受性别和年龄影响的显著变化.
- 这些发现强调了全面分析对B-ALL管理的重要性.
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