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该SARS-CoV-2尖尖蛋白突变探险器:使用一个交互式应用程序,以提高公众对SARS-CoV-2变种的了解

Sarah Iannucci¹, William T Harvey², Joseph Hughes²

¹School of Simulation and Visualisation, The Glasgow School of Art, Glasgow, UK.

Journal of visual communication in medicine

|August 1, 2023

概括

交互式可视化有效地向公众传达SARS-CoV-2尖端蛋白演化和关注的变体 (VOCs). SARS-CoV-2 尖端蛋白突变探索器 (SSPME) 增强了对病毒突变及其影响的理解.

科学领域:

分子生物学分子生物学
病毒学病毒学
科学传播科学传播

背景情况:

随着COVID-19大流行,公众对SARS-CoV-2的兴趣增加了,特别是其尖端蛋白,这是疫苗和免疫反应的关键目标.
SARS-CoV-2 的快速演变导致了具有改变传播能力和疫苗有效性的令人担忧的变体 (VOC).
现有的数据门户网站,如COG-UK/ME,虽然有信息意义,但是为专家受众设计的.

研究的目的:

为了开发一个可访问的图形教育资源,SARS-CoV-2尖端蛋白突变探索器 (SSPME).
使用交互式3D模型和动画来解释SARS-CoV-2关注变体 (VOCs) 的分子生物学.
与现有的专家专注工具相比,评估SSPME的可用性和教育有效性.

主要方法:

开发了SARS-CoV-2尖端蛋白突变探测器 (SSPME) 与交互式3D分子模型和动画.
用户测试SSPME以评估可用性,知识信心和知识获取.
与COG-UK/ME门户网站相比,SSPME的有效性进行比较.

主要成果:

与COG-UK/ME门户相比,SSPME表现出优越的可用性.
使用SSPME的参与者表现出更好的知识信心和更大的知识获取.
交互式可视化显著增强了对与VOCs相关的分子生物学概念的理解.

结论:

交互式可视化是将复杂的分子生物学主题传达给广大受众的有效工具.
在SSPME成功地改善了公众对SARS-CoV-2关注变体 (VOCs) 的理解.
这种方法可用于在卫生危机期间加强公众对科学信息的参与.

关键词:

3D可视化 3D可视化在 COVID-19 疫情中,冠状病毒冠状病毒的新冠病毒.分子生物学分子生物学科学教育科学教育教育.病毒学病毒学

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