在未接受过治疗的人类免疫缺陷病毒感染患者的右心室功能
Bassey Effiong1, Victor Ansa2, Joseph Andy3
1Department of Internal Medicine, University of Uyo Teaching Hospital, Uyo, Nigeria.
Cardiovascular journal of Africa
|August 1, 2023
概括
在开始治疗的HIV阳性患者中,右室功能障碍很常见. 然而,在研究中,CD4计数并不能预测这种功能障碍的严重程度.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 右心室功能障碍与人类免疫缺陷病毒 (HIV) 阳性个体的较差结果有关.
- 在未接受过治疗的HIV阳性患者中,右心室功能障碍的患病率和预测因素需要进一步调查.
研究的目的:
- 为了确定右室内静脉和静脉功能障碍在尚未接受抗逆转录病毒治疗的HIV阳性患者中的患病率.
- 在这个人群中确定右心室功能障碍的预测因子.
主要方法:
- 一项涉及60名艾滋病毒阳性患者和60名艾滋病毒阴性对照者的横截面研究.
- 进行了跨胸腔心声扫描,以评估右心室的缩和放缩功能.
- 在HIV阳性参与者中测量了CD4细胞计数.
主要成果:
- 在11.6%的HIV阳性患者中观察到右心室缩功能障碍,而对照组中则为3.33% (p=0.166).
- 在HIV阳性患者 (15.0%) 中,右心室扩张性功能障碍比对照患者 (1.7%) (p=0.021) 中更为普遍.
- CD4 细胞计数与右心室缩性或腹缩性功能障碍的存在或严重程度没有相关性.
结论:
- 右心室缩和腹缩功能障碍是治疗前未经治疗的艾滋病毒感染个体的常见发现.
- CD4计数和其他测量参数与右心室功能障碍的频率或程度无关.
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