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针对分子光子的强化NIR-II光生物成像的J-聚合策略

Xiaoming Hu^1,2, Caijun Zhu¹, Fengwei Sun²

¹Jiangxi Key Laboratory of Nanobiomaterials, School of Materials Science and Engineering, East China Jiaotong University, Nanchang, 330013, China.

Advanced materials (Deerfield Beach, Fla.)

|August 1, 2023

概括

开发用于第二次近红外 (NIR-II) 窗口的新型J聚合物光体对于先进的深层组织生物成像和生物传感至关重要. 这项工作阐明了制造滑叠J聚合物的分子策略,增强NIR-II排放以改善诊断和治疗方法.

科学领域:

材料科学材料科学材料科学
生物医学工程生物医学工程
有机化学有机化学

背景情况:

第二次近红外 (NIR-II) 光体 (1000-1700nm) 对于深层组织生物成像和生物传感至关重要.
J-聚合物为NIR-II发射提供了卓越的光学性能,可用于瘤检测,血管映射和外科导航.
对结构-性质关系的有限理解阻碍了先进的NIR-II J-聚合物光体的开发.

研究的目的:

阐明分子策略,以形成滑叠的J-聚合物与J型激子合NIR-II发射.
总结和分析用于实现NIR-II J-聚合物的分子调节策略.
为开发新型NIR-II有机光体用于生物成像和发光学提供参考.

主要方法:

对NIR-II J-聚合物的分子调节策略的总结和分析.
对NIR-II生物成像和theranostics的J聚合物最近的报告进行系统审查.
分子结构的阐明,用于滑叠包装图案和J型激子合.

主要成果:

识别关键的分子结构和分子间相互作用的滑叠J聚合物形成.
对影响J聚合物形成和光学性质的外部条件的分析.
编译了NIR-II J聚合物的最新进展,用于生物成像和theranostics.

结论:

特定的分子设计对于实现具有理想的NIR-II排放特性的滑叠J聚合物至关重要.
对结构-财产关系的进一步研究将加速NIR-II J-聚合物的开发.
优化NIR-II J-聚合物对诊断和治疗中的临床应用具有重大前景.

关键词:

在J-聚合物.有机半导体光体是有机的半导体光体.红色偏移的光谱第二次近红外光成像近红外光成像战略设计战略设计

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