在癌症患者中预防和治疗C. difficile
Pedro Puerta-Alcalde1, Carolina Garcia-Vidal, Alex Soriano
1Infectious Disease Department, Hospital Clinic of Barcelona, Barcelona, Spain.
Current opinion in infectious diseases
|August 1, 2023
概括
困难结肠杆菌感染 (CDI) 在癌症患者中很常见,特别是那些患有血液性恶性瘤的人,由于肠道微生物组的破坏. 最佳的治疗和预防策略需要进一步的研究,尽管便微生物群移植有望减少复发.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 困难菌感染 (CDI) 在癌症患者中提出了独特的挑战,包括难以区分殖民和感染以及不清楚的严重程度标准.
- 癌症患者,特别是患有血液性恶性瘤的患者,患有CDI的发病率很高,通常与抗生素,化疗和放射治疗等治疗的肠道微生物组破坏有关.
结论:
- 进一步的研究是必不可少的,以建立清晰的诊断,严重程度分级和治疗指南,用于癌症患者的CDI.
- 经常性CDI是一个重大问题,需要有效的策略来减轻风险.
- 便微生物群移植 (FMT) 显示出降低CDI复发率在这个脆弱人群中的潜力.
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