手持式通用路径扫描源光学连贯性断层扫描血管造影手持式通用路径扫描源光学连贯性断层扫描
Optics letters
|August 1, 2023
概括
一个新的手持式光连贯断层扫描血管造影 (OCTA) 系统提供稳定,快速的皮肤成像. 这种具有成本效益的设备在检测微血管方面具有高灵敏度,有助于临床皮肤查.
科学领域:
- 生物医学光学 生物医学光学
- 医学成像技术 医学成像技术
背景情况:
- 光学连贯断层扫描血管图 (OCTA) 对于可视化微血管结构至关重要.
- 现有的OCTA系统可能很庞大,对环境变化敏感,限制了手持应用.
- 开发紧,稳定的OCTA探头对于点诊断至关重要.
研究的目的:
- 开发一个手持式光学连贯断层扫描血管学 (OCTA) 系统.
- 为了实现临床皮肤查的稳定和快速成像.
- 为了证明系统在体内成像能力的人类皮肤微血管.
主要方法:
- 使用了一种高速 (200 kHz) 扫雷激光.
- 为了提高稳定性,采用双参考通道配置.
- 集成了一个单一的循环器作为一个紧的设计的主要光学元件.
主要成果:
- 达到最低可检测的流速约为0.08mm/s.
- 证明了亚微米包膜稳定性和纳米级阶段变化.
- 在人体中成功成像了体内皮肤结构和微血管.
结论:
- 开发的手持式OCTA系统提供稳定,高灵敏度的成像.
- 共同路径设计确保了手持式使用的成本效益和紧性.
- 这项技术在临床皮肤查和诊断方面具有重大潜力.
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