中等动脉化评分与主要四肢截肢风险增加有关
Alexander D DiBartolomeo1, Sydney E Browder2, Sebouh Bazikian1
1Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Keck Medical Center of University of Southern California, Los Angeles, CA.
Journal of vascular surgery
|August 1, 2023
概括
踏板中枢动脉化 (MAC) 评分有助于预测慢性肢体威胁性缺血症患者的大肢截肢风险. 更高的MAC分数表明风险更高,有助于治疗决策.
科学领域:
- 血管外科 血管外科
- 放射学 放射学是一门学科.
- 足部医学是一门专业.
背景情况:
- 慢性肢体威胁性缺血症 (CLTI) 具有重大肢体截肢的重大风险.
- 中枢动脉化 (MAC) 是一个已知预测CLTI不良结果的预测因素.
- 踏板MAC得分专门评估了红外脉动脉中的化.
研究的目的:
- 为了验证踏板中枢动脉化 (MAC) 评分系统.
- 评估踏板MAC分数在预测主要四肢截肢风险方面的有用性.
- 确认踏板MAC得分在多机构环境中的可复制性和通用性.
主要方法:
- 这是一项对176名为CLTI进行下 inguinal revascularization的患者进行的多机构回顾性研究.
- 踏板MAC得分 (0-5) 由脚X射线分配,然后进行三切断 (0-1,2-4,5).
- 主要结局:6个月大肢体截肢,使用调整的卡普兰-梅尔模型进行分析.
主要成果:
- 总共有184个四肢被分析;14% (26个四肢) 在6个月内经历了重大截肢.
- 踏板MAC得分为5的患者与得分为0-1和2-4的患者相比,患有主要四肢截肢的风险明显更高.
- 总体无截肢生存率在MAC得分较高的患者中较低 (日志排名P = .008).
结论:
- 踏板MAC得分是一种可重现和可概括的,用于测量内动脉疾病的指标.
- 踏板MAC得分可以与伤口,缺血和足部感染 (WIfI) 阶段进行整合.
- 这种综合方法有助于预测CLTI患者的大肢截肢风险.
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