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与结直肠癌相关的突变会损害EphB1激酶的功能

Yunyoung Kim1, Sultan Ahmed1, W Todd Miller2

  • 1Department of Physiology and Biophysics, Stony Brook University, Stony Brook, New York, USA.

The Journal of biological chemistry
|August 1, 2023
PubMed
概括

在EphB1中发生的突变,受体氨酸激酶,降低其活性和瘤抑制功能在结肠直肠癌 (CRC). 这些EphB1突变损害了细胞迁移和细分,这表明在CRC进展中发挥了作用.

关键词:
细胞的分离,细胞的细分.细胞迁移 细胞迁移细胞信号传递是细胞的信号传递.结肠直肠癌是什么意思酶动力学 酶动力学酶突变是一种酶突变.蛋白质净化 蛋白质净化蛋白质的稳定性 蛋白质的稳定性受体氨酸激酶的受体.

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