妊娠糖尿病和不良结果的两步查完成的时间
Sarah A Nazeer1, Han-Yang Chen1, Joycelyn A Cornthwaite1
1Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
American journal of perinatology
|August 1, 2023
概括
在14天内完成妊娠糖尿病 (GDM) 查,而不是在更长时间内完成查,并没有影响新生儿不良结果. 这项研究发现,无论GDM诊断测试完成时间,不存在不良结果的风险增加.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 内分泌学 在内分泌学.
背景情况:
- 孕期糖尿病 (GDM) 查涉及多个步骤,包括葡萄糖挑战测试 (GCT) 和葡萄糖耐受性测试 (GTT).
- 及时完成GDM诊断测试对于适当的管理和减轻潜在的不良妊娠和新生儿后果至关重要.
研究的目的:
- 调查完成两步GDM查过程的时间与新生儿不良结果之间的关联.
- 为了确定在异常1小时GCT后延迟完成3小时GTT是否会影响新生儿的健康.
主要方法:
- 在一个学术医院系统进行GDM查的单个,非异常怀孕的回顾性队列研究.
- 在3小时GTT完成后,在≤14天内完成3小时GTT的个体之间的新生儿结局的比较,与1小时GCT后的>14天相比.
- 多变量波桑回归模型用于计算初级和二级结果的调整相对风险 (aRR) 和95%置信区间 (CI).
主要成果:
- 在完成两步查的313个人中,54.6%在14天内完成了3小时的GTT.
- 新生儿综合不良后果的总比率为44.1%.
- 在 ≤14天和 >14天完成组之间,在初级组合不良新生儿结局 (aRR=1.11,95% CI=0.81-1.52) 或次要结局中没有显著差异.
结论:
- 两步GDM查的完成时间,特别是GCT和GTT之间的间隔,与新生儿不良结果的增加率无关.
- 这些发现表明,延迟在14天内完成GDM诊断工作并不会对这一队列中产周健康产生负面影响.
相关概念视频
01:22Diabetes Mellitus: Type 2 and Gestational
2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
01:20Pathophysiology of Diabetes
993
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
993
01:15Diabetes: Symptoms, Diagnosis, and Complications
593
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
593
01:14SBAR II: Application of SBAR
4.5K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.5K
01:36Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K
01:15Diabetes: Management and Pharmacotherapy
313
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
313