异质造血细胞移植后的晚期并发症:初级保健医生可以做些什么
Lauren M Granat1, Mariah Ondeck2, Bennett Osantowski2
1Chief Resident, Department of Internal Medicine, Cleveland Clinic, Cleveland, OH granatl2@ccf.org.
Cleveland Clinic journal of medicine
|August 1, 2023
概括
初级保健医生对于在异质造血细胞移植 (HCT) 后的长期并发症的管理至关重要. 本综述涵盖了诸如慢性移植与宿主疾病和二次癌症等常见问题,以及健康维护指南.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 初级医疗保健医学 一级医疗保健医学
背景情况:
- 异质造血细胞移植 (HCT) 幸存者面临着显著的长期健康风险.
- 初级保健医生 (PCP) 对于在HCT后持续的患者护理至关重要.
研究的目的:
- 审查HCT后常见的长期并发症.
- 引导PCP识别和管理这些并发症.
- 为HCT幸存者提供健康维护和查建议.
主要方法:
- 关于常见的HCT并发症的文献综述.
- 综合当前关于HCT后护理的证据.
- 健康维护策略的总结.
主要成果:
- 常见的并发症包括慢性移植对宿主疾病,心血管,代谢,内分泌,类风湿,骨科,传染病,神经和认知问题.
- 增加二次恶性瘤和精神疾病的风险.
- 生活质量和性健康的恶化是常见的.
结论:
- PCP需要意识到各种HCT并发症.
- 积极的管理和查对于HCT幸存者的健康至关重要.
- 这一审查为PCP主导的对HCT幸存者的综合护理提供了一个框架.
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