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Updated: Jul 20, 2025

Author Spotlight: Exploring the Role of Unfolded Protein Response in HIV-1 Replication and Infectivity
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通过VAPB介导的ER准稳定了IRS-1信号体,以调节胰岛素/IGF信号传递

Xiu Kui Gao1,2,3, Zu Kang Sheng4,5, Ye Hong Lu4,5

  • 1Department of Biochemistry and Department of Orthopaedic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. gaoxiukui@zju.edu.cn.

Cell discovery
|August 1, 2023
PubMed
概括

胰岛素受体基质1 (IRS-1) 的稳定性取决于内分泌网膜 (ER) 的向. 囊泡相关膜蛋白相关蛋白B (VAPB) 结合IRS-1,将其向ER并保持其稳定性.

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