当代儿科人口中心肺运动测试参数的参考值
Pascal Amedro1,2,3, Stefan Matecki4,5, Taissa Pereira Dos Santos6
1Department of Paediatric and Congenital Cardiology, M3C National Reference Centre, Bordeaux University Hospital, 1 Avenue Magellan, 33604, Pessac, France. pascal.amedro@chu-bordeaux.fr.
本研究为关键心肺运动测试 (CPET) 参数建立了儿科参考Z-score,有助于评估儿童的健康和健康状况.
科学领域:
- 儿科运动生理学 运动生理学
- 心肺功能的评估评估.
- 生物统计学在健康研究中的应用
背景情况:
- 心肺运动测试 (CPET) 越来越多地用于评估儿科健康.
- 之前的研究已经确定了儿童VO2max的Z-score.
- 对于儿童的其他CPET参数缺乏验证的参考值.
研究的目的:
- 为了确定主要循环人体表CPET参数的儿科参考Z-score值.
- 用同一个队列扩展现有的VO2max参考值.
- 为评估正常和极端体重的儿童提供工具.
主要方法:
- 对909名5至18岁的健康儿童进行了横截面研究.
- 应用线性,二次性和多项式回归来识别Z分数.
- 基于人类参数的分析,包括性别,年龄,身高,体重和BMI.
主要成果:
- 为最大CPET参数提供Z分数:心率,呼吸交换比率,工作负载和氧气脉冲.
- 已建立的Z-score用于次最大CPET参数:通风无氧值,VE/VCO2斜率和氧吸收效率斜率.
- 对于最大通风器CPET参数的定义Z-score:潮体积,呼吸率,呼吸储备和通风器等效.
结论:
- 定义了主要循环人体表CPET参数的儿科参考Z-分数.
- 这些Z分数补充了现有的VO2max值,适用于所有体重的儿童.
- 这些发现支持在预后研究和临床试验中使用心肺健康结果的儿科研究.
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