在帕金森病的选择阶段使用趋势变化分析进行平衡评估
Piotr Wodarski1, Jacek Jurkojć2, Justyna Michalska3
1Department of Biomechatronics, Faculty of Biomedical Engineering, Silesian University of Technology, Gliwice, Poland. piotr.wodarski@polsl.pl.
Journal of neuroengineering and rehabilitation
|August 1, 2023
概括
帕金森病 (PD) 改变平衡策略,增加患者的趋势变化指数 (TCI) 和速度 (TCI_dV). 这种对压力中心 (COP) 信号的新分析有助于评估PD进展和平衡控制.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
- 生物物理学的生物物理.
背景情况:
- 帕金森病 (PD) 的特点是由于改变平衡策略和影响姿势控制的反射障碍引起的平衡障碍.
- 静止时的压力中心 (COP) 位移信号对于分析这些平衡控制变化至关重要.
研究的目的:
- 调整股票市场趋势变化分析指数以评估使用COP信号评估帕金森病进展情况.
- 研究与健康对照组相比,在PD患者中保持平衡策略的变化.
主要方法:
- 分析了30名PD患者,40名老年人和20名年轻人静静地站立时的COP移位信号.
- 计算趋势变化指数 (TCI),包括趋势变化之间的平均时间 (TCI_dT),平均位移 (TCI_dS) 和平均速度 (TCI_dV).
主要成果:
- 与年龄相匹配的对照组相比,PD患者的TCI值显著更高 (p < 0.05).
- PD患者显示TCI_dS增加 (2-5毫米),主要导致TCI_dV升高.
- 在不同平均COP速度的组之间观察到TCI_dT的统计学上显著差异.
结论:
- 基于健康参与者的TCI和TCI_dV开发的指数可以支持PD诊断.
- 该研究发现,PD患者TCI_dV增加的结果是TCI_dT或TCI_dS的变化.
- 这种方法为PD对平衡策略的影响提供了新的见解,超越了目前的分析局限性.
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