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在患有多发性硬化症的老年人中引起体积和冷漠的症状
Sarah E Cote1, Mark E Wagshul2, Fredrick W Foley1
1Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Multiple sclerosis (Houndmills, Basingstoke, England)
|August 2, 2023
概括
患有多发性硬化症 (MS) 的老年人经历了更多的冷漠. 在MS患者下部尾状核体积与增加的冷漠有关,与对照组不同.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 在多发性硬化症 (MS) 和其他神经疾病中,冷漠是普遍存在的.
- 在患有多发性硬化症 (OAMS) 的老年人中,冷漠的机制仍未得到充分研究.
研究的目的:
- 与对照组相比,调查OAMS中的冷漠性流行率.
- 检查OAMS中冷漠和尾状核体积之间的关系.
主要方法:
- 对67名OAMS和74名对照进行了脑部MRI,认知,心理和运动评估.
- 漠不关心被测量使用老年抑郁症尺度的漠不关心子表.
主要成果:
- OAMS报告的冷漠度得分明显高于对照组.
- 在OAMS中,减少尾状核体积和冷漠之间观察到更强烈的关联.
- 左下和右尾状核体积与更大的冷漠度相关,特别是在OAMS.
结论:
- 容易患MS的尾状核可能在OAMS中对 apathía的发展和严重程度起作用.
- 这些发现突出了尾状核作为理解和管理OAMS无动于衷的潜在目标.
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